2020

Sayols S, Klassek J, Werner C, Möckel S, Ritz S, Mendez-Lago M and Soshnikova N (2020) Signalling codes for the maintenance and lineage commitment of embryonic gastric epithelial progenitors. Development, 147:dev188839 Link

Schneckenburger H, Richter V, Gelleri M, Ritz S, Vaz Pandolfo R, Schock F, Hase VJ, Birk U and Cremer C (2020) High-resolution deep view microscopy of cells and tissues. Quantum Electron, 50:2–8 Link

Schwirz J*, Yan Y*^,#, Franta Z and Schetelig MF^# (2020) Bicistronic expression and differential localization of proteins in insect cells and Drosophila suzukii using picornaviral 2A peptides. Insect Biochem Mol Biol, 119:103324 (*indicates joint contribution, ^#indicates joint correspondance) Link

Wong RP, García-Rodríguez N, Zilio N, Hanulová M and Ulrich HD (2020) Processing of DNA Polymerase-Blocking Lesions during Genome Replication Is Spatially and Temporally Segregated from Replication Forks. Mol Cell, 77:3–16.e4 Link

2019

Bluhm A, Viceconte N, Li F, Rane G, Ritz S, Wang S, Levin M, Shi Y, Kappei D and Butter F (2019) ZBTB10 binds the telomeric variant repeat TTGGGG and interacts with TRF2. Nucleic Acids Res, 47:1896–1907 Link

Liskayová G, Hubčík L, Búcsi A, Fazekaš T, Martínez JC, Devínsky F, Pisárčik M, Hanulová M, Ritz S and Uhríková D (2019) pH-Sensitive N,N-Dimethylalkane-1-amine N-Oxides in DNA delivery: From structure to transfection efficiency. Langmuir, 35:13382–13395 Link

Liu X*, Chen SY*, Chen Q, Yao X, Gelléri M, Ritz S, Kumar S, Cremer C, Landfester K, Müllen K, Parekh S, Narita A and Bonn M (2019) Nanographenes: Ultrastable, switchable, and bright probes for super-resolution microscopy. Angew Chemie Int Ed, 59:496–502 (*indicates joint contribution) Link

Schultheis D, Schwirz J and Frasch M (2019) RNAi screen in Tribolium reveals involvement of F-BAR proteins in myoblast fusion and visceral muscle morphogenesis in insects. G3-Genes Genomes Genet, 9:1141–1151 Link

Schultheis D, Weißkopf M, Schaub C, Ansari S, Dao VA, Grossmann D, Majumdar U, Hakeemi MS, Troelenberg N, Richter T, Schmitt-Engel C, Schwirz J, Ströhlein N, Teuscher M, Bucher G and Frasch M (2019) A large scale systemic RNAi screen in the red flour beetle Tribolium castaneum identifies novel genes involved in insect muscle development. G3-Genes Genomes Genet, 9:1009–1026 Link

2018

Hubčík L, Galliková D, Pullmannová P, Lacinová Ľ, Sulová Z, Hanulová M, Funari SS, Devínsky F and Uhríková D (2018) DNA-DOPE-gemini surfactants complexes at low surface charge density: From structure to transfection efficiency.Gen Physiol Biophys, 37:57–69 Link

Momper R, Steinbrecher J, Dorn M, Rörich I, Bretschneider S, Tonigold M, Ramanan C, Ritz S, Mailänder V, Landfester K and Bannwarth MB (2018) Enhanced photoluminescence properties of a carbon dot system through surface interaction with polymeric nanoparticles.J Colloid Interface Sci, 518:11–20 Link

Reinholz J, Diesler C, Schöttler S, Kokkinopoulou M, Ritz S, Landfester K and Mailänder V (2018) Protein machineries defining pathways of nanocarrier exocytosis and transcytosis.Acta Biomater, 71:432–443 Link

Seiwert D, Witt H, Ritz S, Janshoff A and Paulsen H (2018) The nonbilayer lipid MGDG and the major light-harvesting complex (LHCII) promote membrane stacking in supported lipid bilayers.Biochemistry, 57:2278–2288 Link

2017

Landgraf L, Nordmeyer D, Schmiel P, Gao Q, Ritz S, Gebauer JS, Graß S, Diabaté S, Treuel L, Graf C, Rühl E, Landfester K, Mailänder V, Weiss C, Zellner R and Hilger I (2017) Validation of weak biological effects by round robin experiments: Cytotoxicity/biocompatibility of SiO₂ and polymer nanoparticles in HepG2 cells. Sci Rep, 7:4341 Link

Ng DYW, Vill R, Wu Y, Koynov K, Tokura Y, Liu W, Sihler S, Kreyes A, Ritz S, Barth H, Ziener U and Weil T (2017) Directing intracellular supramolecular assembly with N-heteroaromatic quaterthiophene analogues. Nat Commun, 8:1850 Link

2016

Kaloyanova S, Zagranyarski Y, Ritz S, Hanulová M, Koynov K, Vonderheit A, Müllen K and Peneva K (2016) Water-soluble NIR-absorbing rylene chromophores for selective staining of cellular prganelles.J Am Chem Soc, 138:2881–2884 Link

Liu W, Naydenov B, Chakrabortty S, Wuensch B, Hübner K, Ritz S, Cölfen H, Barth H, Koynov K, Qi H, Leiter R, Reuter R, Wrachtrup J, Boldt F, Scheuer J, Kaiser U, Sison M, Lasser T, Tinnefeld P, Jelezko F, Walther P, Wu Y and Weil T (2016) Fluorescent nanodiamond-gold hybrid particles for multimodal optical and electron microscopy cellular imaging. Nano Lett, 16:6236–6244 Link

2015

Lerch S*, Ritz S*, Bley K, Messerschmidt C, Weiss CK, Musyanovych A, Landfester K and Mailänder V (2015) Nanoprobing the acidification process during intracellular uptake and trafficking.Nanomedicine, 11:1585–1596 (*indicates equal contribution) Link

Zaba C, Ritz S, Tan C-WD, Zayni S, Müller M, Reuning U and Sinner E-K (2015) Functional cell adhesion receptors (integrins) in polymeric architectures. ChemBioChem, 16:1740–1743 Link

2014

Boutter J, Huang Y, Marovca B, Vonderheit A, Grotzer MA, Eckert C, Cario G, Wollscheid B, Horvath P, Bornhauser BC and Bourquin J-P (2014) Image-based RNA interference screening reveals an individual dependence of acute lymphoblastic leukemia on stromal cysteine support.Oncotarget, 5:11501–11512 Link

Holloschi A, Ritz S, Schäfer I and Kioschis P (2014) Analysis of huntingtin aggregation by fluorescence and FRET microscopy. Pages 217–215 in: Microscopy: Advances in scientific research and education, vol. 1 (ed. Méndez-Vilas A), Formatex, Badajoz  Link

Rämö P, Drewek A, Arrieumerlou C, Beerenwinkel N, Ben-Tekaya H, Cardel B, Casanova A, Conde-Alvarez R, Cossart P, Csúcs G, Eicher S, Emmenlauer M, Greber U, Hardt W-D, Helenius A, Kasper C, Kaufmann A, Kreibich S, Kühbacher A, Kunszt P, Low SH, Mercer J, Mudrak D, Muntwiler S, Pelkmans L, Pizarro-Cerdá J, Podvinec M, Pujadas E, Rinn B, Rouilly V, Schmich F, Siebourg-Polster J, Snijder B, Stebler M, Studer G, Szczurek E, Truttmann M, von Mering C, Vonderheit A, Yakimovich A, Bühlmann P and Dehio C (2014) Simultaneous analysis of large-scale RNAi screens for pathogen entry.BMC Genomics, 15:1162 Link

2013

Persch N, Elhayek A, Welk M, Bruhn A, Grewenig S, Böse K, Kraegeloh A and Weickert J (2013) Enhancing 3-D cell structures in confocal and STED microscopy: A joint model for interpolation, deblurring and anisotropic smoothing. Meas Sci Technol, 24:125703 Link

2021

Chongtham MC, Butto T, Mungikar K, Gerber S and Winter J (2021) INTACT vs. FANS for cell-type-specific nuclei sorting: a comprehensive qualitative and quantitative comparison. Int J Mol Sci, 22:5335

Jin E*, Yang Q*, Cheng-Wei J, Chen Q, Landfester K, Bonn M^#, Müllen K^#, Liu X^# and Narita A^# (2021) A highly luminescent nitrogen-doped nanographene as an acid- and metal-sensitive fluorophore for optical imaging.  J Am Chem Soc, accepted (*indicates joint contribution, ^#indicates joint correspondance)

Perez-Borrajero C, Podvalnaya N*, Holleis K*, Lichtenberger R, Karaulanov E, Simon B, Basquin J, Hennig J^#, Ketting RF^# and Falk S^# (2021) Structural basis of PETISCO complex assembly during piRNA biogenesis in C. elegans. Genes Dev, 35:1304-1323 (*indicates joint contribution, ^#indicates joint correspondence)

Placentino M, Jesus Domingues AM, Schreier J, Dietz S, Hellmann S, Albuquerque BF, Butter F and Ketting RF (2021) Intrinsically disordered protein PID‐2 modulates Z granules and is required for heritable piRNA‐induced silencing in the Caenorhabditis elegans embryo. EMBO J, 40:e105280

2020

Dold A*, Han H*, Liu N*, Hildebrandt A, Brüggemann M, Rücklé C, Hänel H, Busch A, Beli P, Zarnack K, König J, Roignant JY^# and Lasko P^# (2020) Makorin 1 controls embryonic patterning by alleviating Bruno1-mediated repression of oskar translation. PLOS Genet, 16:e1008581 (*indicates joint contribution, ^#indicates joint correspondence)

Redl S*, de Jesus Domingues AM*, Caspani E, Möckel S, Salvenmoser W, Mendez-Lago M and Ketting RF (2021) Extensive nuclear gyration and pervasive non-genic transcription during primordial germ cell development in zebrafish. Development, 148:dev193060 (*indicates joint contribution)

Vydzhak O*, Bender K*, Klermund J, Busch A, Reimann S and Luke B (2020) Checkpoint adaptation in recombination-deficient cells drives aneuploidy and resistance to genotoxic agents. DNA Repair, 95:102939 (*indicates joint contribution)

2019

Arab K, Karaulanov E, Musheev M, Trnka P, Schäfer A, Grummt I^# and Niehrs C^# (2019) GADD45A binds R-loops and recruits TET1 to CpG island promoters. Nat Genet, 51:217–223 (^#indicates joint correspondence)

Gothe HJ, Bouwman BAM*, Gusmao EG*, Piccinno R, Petrosino G, Sayols S, Drechsel O, Minneker V, Josipovic N, Mizi A, Nielsen CF, Wagner EM, Takeda S, Sasanuma H, Hudson DF, Kindler T, Baranello L, Papantonis A*, Crosetto N* and Roukos V (2019) Spatial chromosome folding and active transcription drive DNA fragility and formation of oncogenic MLL translocations. Mol Cell, 75:267-283.e12 (*indicates joint contribution)

Gronke K, Hernández PP, Klose CSN, Kofoed-Branzk M, Guendel F, Witkowski M, Tizian C, Amann L, Schumacher F, Glatt H, Triantafyllopoulou A and Diefenbach A (2019) Interleukin-22 protects intestinal stem cells against genotoxic stress.Nature, 566:249–253

Han D*, Schomacher L*^#, Schüle KM*, Mallick M, Musheev MU, Karaulanov E, Krebs L, von Seggern A and Niehrs C^# (2019) NEIL1 and NEIL2 DNA glycosylases protect neural crest development against mitochondrial oxidative stress. eLife, 8:e49044 (*indicates joint contribution, ^#indicates joint correspondence)

Hildebrandt A, Brüggemann M, Rücklé C, Boerner S, Heidelberger JB, Busch A, Hänel H, Voigt A, Möckel MM, Ebersberger S, Scholz A, Dold A, Schmid T, Ebersberger I, Roignant JY, Zarnack K^#, König J^# and Beli P^# (2019) The RNA-binding ubiquitin ligase MKRN1 functions in ribosome-associated quality control of poly(A) translation. Genome Biol, 20:216 (^#indicates joint correspondence) 

Schüle KM^*, Leichsenring M^*, Andreani T, Vastolo V, Mallick M, Musheev MU, Karaulanov E and Niehrs C (2019) GADD45 promotes locus-specific DNA demethylation and 2C cycling in embryonic stem cells. Genes Dev, 33:782–798 (^*indicates joint contribution)

2018

Almeida MV, Dietz S, Redl S, Karaulanov E, Hildebrandt A, Renz C, Ulrich HD, König J, Butter F and Ketting RF (2018) GTSF‐1 is required for formation of a functional RNA‐dependent RNA polymerase complex in Caenorhabditis elegans. EMBO J, 37: e99325

Fritzsch C*, Baumgärtner S*, Kuban M, Steinshorn D, Reid G^# and Legewie S^# (2018) Estrogen‐dependent control and cell‐to‐cell variability of transcriptional bursting. Mol Syst Biol, 14: e7678 (*indicates joint contribution,^#indicates joint correspondence)

García‐Rodríguez N, Morawska M, Wong RP, Daigaku Y and Ulrich HD (2018) Spatial separation between replisome‐ and template‐induced replication stress signaling. EMBO J, 37: e98369

Heidelberger JB, Voigt A, Borisova ME, Petrosino G, Ruf S, Wagner SA and Beli P (2018) Proteomic profiling of VCP substrates links VCP to K6‐linked ubiquitylation and c‐Myc function.EMBO Rep, 19:187-381

Kaymak A, Sayols S, Papadopoulu T and Richly H (2018) Role for the transcriptional activator ZRF1 in early metastatic events in breast cancer progression and endocrine resistance. Oncotarget, 9: 28666–28690

Moscariello P, Ng DYW, Jansen M, Weil T, Luhmann HJ and Hedrich J (2018) Brain delivery of multifunctional dendrimer protein bioconjugates. Adv Sci, 5:1700897

Nayak T, Trotter J and Sakry D (2018) The intracellular cleavage product of the NG2 proteoglycan modulates translation and cell-cycle kinetics via effects on mTORC1/FMRP Signaling.Front Cell Neurosci, 12:231

Roovers EF*, Kaaij LJT*, Redl S, Bronkhorst AW, Wiebrands K, de Jesus Domingues AM, Huang HY, Han CT, Riemer S, Dosch R, Salvenmoser W, Grün D, Butter F, van Oudenaarden A and Ketting RF (2018) Tdrd6a regulates the aggregation of Buc into functional subcellular compartments that drive germ cell specification. Dev Cell, 46:285–301.e9 (*indicates joint contribution)

Schink A, Neumann J, Leifke AL, Ziegler K, Fröhlich-Nowoisky J, Cremer C, Thines E, Weber B, Pöschl U, Schuppan D and Lucas K (2018) Screening of herbal extracts for TLR2- and TLR4-dependent anti-inflammatory effects. PLoS ONE, 13:e0203907

Tiwari N, Pataskar A, Péron S, Thakurela S, Sahu SK, Figueres-Oñate M, Marichal N, López-Mascaraque L, Tiwari VK and Berninger B (2018) Stage-Specific transcription factors drive astrogliogenesis by remodeling gene regulatory landscapes.Cell Stem Cell, 23: 557–571.e8

Zimmermann T, Maroso M, Beer A, Baddenhausen S, Ludewig S, Fan W, Vennin C, Loch S, Berninger B, Hofmann C, Korte M, Soltesz I, Lutz B and Leschik J (2018) Neural stem cell lineage-specific cannabinoid type-1 receptor regulates neurogenesis and plasticity in the adult mouse hippocampus. Cerebral Cortex, 28, 4458–4471

2017

Blanquie O, Yang J-W, Kilb W, Sharopov S, Sinning A and Luhmann HJ (2017) Electrical activity controls area-specific expression of neuronal apoptosis in the developing mouse cerebral cortex. eLife, 6: 1-21

Chitale S and Richly H (2017) Nuclear organization of nucleotide excision repair is mediated by RING1B dependent H2A-ubiquitylation. Oncotarget, 8: 30870-30887

Dinges N, Morin V, Kreim N, Southall TD and Roignant JY (2017) Comprehensive characterization of the complex lola locus reveals a novel role in the octopaminergic pathway via tyramine beta-hydroxylase regulation. Cell Rep, 21:2911–2925

Dzama MM, Nigmatullina L, Sayols S, Kreim N and Soshnikova N (2017) Distinct populations of embryonic epithelial progenitors generate Lgr5+ intestinal stem cells. Dev Biol, 432: 258-264

Graf M, Bonetti D, Lockhart A, Serhal K, Kellner V, Maicher A, Jolivet P, Teixeira MT and Luke B (2017) Telomere length determines TERRA and R-Loop regulation through the cell cycle. Cell, 170: 72-85

Kazakevych J, Sayols S, Messner B, Krienke C and Soshnikova N (2017) Dynamic changes in chromatin states during specification and differentiation of adult intestinal stem cells. Nucleic Acids Res, 45: 5770-5784

Lebedeva S, de Jesus Domingues AM, Butter F and Ketting RF (2017) Characterization of genetic loss-of-function of Fus in zebrafish. RNA Biol, 14: 29-35

Navandar M, Garding A, Kumar Sahu S, Pataskar A, Schick S and Tiwari VK (2017) ERK signalling modulates epigenome to drive epithelial to mesenchymal transition. Oncotarget, 8: 29269-29281

Nigmatullina L, Norkin M, Dzama MM, Messner B, Sayols S and Soshnikova N (2017) Id2 controls specification of Lgr5(+) intestinal stem cell progenitors during gut development. EMBO J, 36: 869-885

Sahu SK, Tiwari N, Pataskar A, Zhuang Y, Borisova M, Diken M, Strand S, Beli P and Tiwari VK (2017) FBXO32 promotes microenvironment underlying epithelial-mesenchymal transition via CtBP1 during tumour metastasis and brain development. Nat Commun, 8: 1523

Szczurek A, Klewes L, Xing J, Gourram A, Birk U, Knecht H, Dobrucki JW, Mai S and Cremer C (2017) Imaging chromatin nanostructure with binding-activated localization microscopy based on DNA structure fluctuations. Nucleic Acids Res, 45: e56

Wilhelm T, Byrne J, Medina R, Kolundžić E, Geisinger J, Hajduskova M, Tursun B and Richly H (2017) Neuronal inhibition of the autophagy nucleation complex extends life span in post-reproductive C. elegans. Genes Dev, 31: 1561-1572

2016

Blanquie O, Liebmann L, Hübner CA, Luhmann HJ and Sinning A (2016) NKCC1-mediated GABAergic signaling promotes postnatal Cell death in neocortical Cajal-Retzius cells. Cereb Cortex, 27: 1644-1659

Kaymak A and Richly H (2016) Zrf1 controls mesoderm lineage genes and cardiomyocyte differentiation. Cell Cycle, 15: 3306-3317

2015

Hirsch M and Helm M (2015) Live cell imaging of duplex siRNA intracellular trafficking. Nucleic Acids Res, 43: 4650-60

Kirmes I, Szczurek A, Prakash K, Charapitsa I, Heiser C, Musheev M, Schock F, Fornalczyk K, Ma D, Birk U, Cremer C and Reid G (2015) A transient ischemic environment induces reversible compaction of chromatin. Genome Biology, 16: 246

Roovers EF, Rosenkranz D, Mahdipour M, Han CT, He N, de Sousa Lopes SMC, van der Westerlaken LA, Zischler H, Butter F, Roelen BA and Ketting RF (2015) Piwi proteins and piRNAs in mammalian oocytes and early embryos. Cell Reports, 10: 2069-2082

Sahu SK, Garding A, Tiwari N, Thakurela S, Toedling J, Gebhard S, Ortega F, Schmarowski N, Berninger B, Nitsch R, Schmidt M and Tiwari V (2015) JNK-dependent gene regulatory circuitry governs mesenchymal fate. EMBO J, 34: 2162-2181. DOI: 10.15252/embj.201490693

Sakry D, Yigit H, Dimou L and Trotter J (2015) Oligodendrocyte precursor cells synthesize neuromodulatory factors. PLoS One, 10: e0127222

Stangenberg R, Wu Y, Hedrich J, Kurzbach D, Wehner D, Weidinger G, Kuan SL, Jansen MI, Jelezko F, Luhmann HJ, Hinderberger D, Weil T and Müllen K (2015) A polyphenylene dendrimer drug transporter with precisely positioned amphiphilic surface patches. Adv Healthc Mater, 4: 377-384

2014

Bühler J, Gietzen S, Reuter A, Kappel C, Fischer K, Decker S, Schäffel D, Koynov K, Bros M, Tubbe I, Grabbe S and Schmidt M (2014) Selective uptake of cylindrical poly(2-oxazoline) brush-antidec205 antibody-ova antigen conjugates into dec-positive dendritic cells and subsequent t-cell activation. Chemistry, 20: 12405-12410

Fritz T, Hirsch M, Richter FC, Müller SS, Hofmann AM, Rusitzka KAK, Markl J, Massing U, Frey H and Helm M (2014) Click modification of multifunctional liposomes bearing hyperbranched polyether chains. Biomacromolecules, 15: 2440-2448

Hamm R, Chen YR, Seo EJ, Zeino M, Wu CF, Müller R, and Yang NS and Efferth T (2014) Induction of cholesterol biosynthesis by archazolid B in {T24} bladder cancer cells. Biochem Pharmacol, 91: 18-30

Hamm R, Zeino M, Frewert S and Efferth T (2014) Up-regulation of cholesterol associated genes as novel resistance mechanism in glioblastoma cells in response to archazolid B. Toxicol Appl Pharmacol, 281: 78-86

Malone CD, Mestdagh C, Akhtar J, Kreim N, Deinhard P, Sachidanandam R, Treisman J and Roignant JY (2014) The exon junction complex controls transposable element activity by ensuring faithful splicing of the piwi transcript. Genes Dev, 28: 1786-1799

2013

Thakurela S, Garding A, Jung J, Schübeler D, Burger L and Tiwari VK (2013) Gene regulation and priming by topoisomerase IIα in embryonic stem cells. Nat Commun, 4: 2478

Tiwari N, Tiwari V, Waldmeier L, Balwierz P, Arnold P, Pachkov M, Meyer-Schaller N, Schübeler D, van Nimwegen E and Christofori G (2013) Sox4 is a master regulator of epithelial-mesenchymal transition by controlling Ezh2 expression and epigenetic reprogramming. Cancer Cell, 23: 768-783

Zehender CM, Librizzi L, Hedrich J, Bauer NM, Angamo EA, De Curtis M and Luhmann HJ (2013) Moderate hypoxia followed by reoxygenation results in blood-brain barrier breakdown via oxidative stress-dependent tight-junction protein disruption. PLoS One, 8: e82823

Zehender CM, Tsohataridis S, Luhmann HJ and Yang JW (2013) Developmental switch inneurovascular coupling in the immature rodent barrel cortex. PLoS One, 8: e80749

Zehender CM, Wedler HE and Luhmann HJ (2013) A novel in vitro model to study pericytes in the neurovascular unit of the developing cortex. PLoS One, 8: e81637

2012

Gierl MS, Gruhn H, von Seggern A, Maltry N and Niehrs C (2012) GADD45G functions in male sex determination by promoting p38 signaling and sry expression. Dev Cell, 23: 1032-1042