Publications co-authored by the Microscopy Core Facility
2023
Bueno D*, Narayan Dey P*, Schacht T*, Wolf C, Wüllner V, Morpurgo E, Rojas-Charry L, Sessinghaus L, Leukel P, Sommer C, Radyushkin K, Florin L, Baumgart J, Stamm P, Daiber A, Horta G, Nardi L, Vasic V, Schmeisser MJ, Hellwig A, Oskamp A, Bauer A, Anand R, Reichert AS, Ritz S, Nocera G, Jacob C, Peper J, Silies M, Frauenknecht KBM, Schäfer MKE and Methner A (2023) NECAB2 is an endosomal protein important for striatal function. Free Radic Biol Med, 208:643–656 (*indicates joint contribution) Link
Chapman KB*, Filipsky *F, Peschke N, Gelléri M, Weinhardt V, Braun A, Hausmann M* and Cremer C* (2023) A comprehensive method to study the DNA’s association with lamin and chromatin compaction in intact cell nuclei at super resolution. Nanoscale, 15:742–756 (*indicates joint contribution) Link
Gelléri M*,#, Chen SY*, Hübner B, Neumann J, Kröger O, Sadlo F, Imhoff J, Hendzel MJ, Cremer M, Cremer T, Strickfaden H# and Cremer C# (2023) True-to-scale DNA-density maps correlate with major accessibility differences between active and inactive chromatin. Cell Rep, 42:112567 (*indicates joint contribution, #indicates joint correspondence) Link
Ghanam J*, Chetty VK*, Zhu X, Liu X, Gelléri M, Barthel L, Reinhardt D, Cremer C# and Thakur BK# (2023) Single molecule localization microscopy for studying small extracellular vesicles. Small, 19:e2205030 (*indicates joint contribution, #indicates joint correspondence) Link
Jayawardena I, Turunen P, Garms BC, Rowan A, Corrie S and Grøndahl L (2023) Evaluation of techniques used for visualisation of hydrogel morphology and determination of pore size distributions. Mater Adv, 4:669–682 Link
Rosellini M, Turunen P and Efferth T (2023) Impact of plastic-related compounds on P-glycoprotein and breast cancer resistance protein in vitro. Molecules, 28:2710 Link
Wang Z, Lauko J, Kijas AW, Gilbert EP, Turunen P, Yegappan R, Zou D, Mata J and Rowan AE (2023) Snake venom-defined fibrin architecture dictates fibroblast survival and differentiation. Nat Commun, 14:1029 Link
2022
Chetty VK, Ghanam J, Anchan S, Reinhardt K, Brenzel A, Gelléri M, Cremer C, Grueso-Navarro E, Schneider M, von Neuhoff N, Reinhardt D, Jablonska J, Nazarenko I and Thakur BK (2022) Efficient small extracellular vesicles (EV) isolation method and evaluation of EV-associated DNA role in cell-cell communication in cancer. Cancers, 14:2068 Link
Cordero M, Ruiz C, Palacio DA, Turunen P, Rowan A and Urbano BF (2022) Effect of low aspect ratio one-dimensional nanoparticles on properties of photocrosslinked alginate nanocomposite hydrogels. Int J Biol Macromol, 204:635–643 Link
Fleischer MI, Röhrig N, Raker VK, Springer J, Becker D, Ritz S, Bros M, Stege H, Haist M, Grabbe S, Haub J, Becker C, Reyda S, Disse J, Schmidt T, Mahnke K, Weiler H, Ruf W# and Steinbrink K# (2022) Protease- and cell type–specific activation of protease-activated receptor 2 in cutaneous inflammation. J Thromb Haemost, 20:2823–2836 (#indicates joint correspondence) Link
Gelléri M, Chen SY, Szczurek A, Hübner B, Sterr M, Neumann J, Kröger O, Sadlo F, Imhoff J, Markaki Y, Hendzel MJ, Cremer M, Cremer T, Strickfaden H and Cremer C (2022) True-to-scale DNA-density maps correlate with major accessibility differences between active and inactive chromatin. BioRxiv, 42:112567 Link
Rose R, Peschke N, Nigi E, Gelléri M, Ritz S, Cremer C, Luhmann HJ# and Sinning A# (2022) Chromatin compaction precedes apoptosis in developing neurons.Commun Biol, 5:797 (#indicates joint correspondence) Link
Wolf C, Pouya A, Bitar S, Pfeiffer A, Bueno D, Rojas-Charry L, Arndt S, Gomez-Zepeda D, Tenzer S, Bello FD, Vianello C, Ritz S, Schwirz J, Dobrindt K, Peitz M, Hanschmann EM, Mencke P, Boussaad I, Silies M, Brüstle O, Giacomello M, Krüger R and Methner A (2022) GDAP1 loss of function inhibits the mitochondrial pyruvate dehydrogenase complex by altering the actin cytoskeleton. Commun Biol, 5:541 Link
2021
Lang F*, Contreras-Gerenas MF*, Gelléri M, Neumann J, Kröger O, Sadlo F, Berniak K, Marx A, Cremer C#, Wagenknecht HA# and Allgayer H# (2021) Tackling Tumour Cell Heterogeneity at the Super-Resolution Level in Human Colorectal Cancer Tissue. Cancers (Basel), 13:3692 (*indicates joint contribution, #indicates joint correspondence) Link
Ruiz de Azua I*, Martin-Garcia E*, Domingo-Rodriguez L, Aparisi Rey A, Pascual Cuadrado D, Islami L, Turunen P, Remmers F, Lutz B and Maldonado R (2021) Cannabinoid CB1 receptor in dorsal telencephalic glutamatergic neurons drives overconsumption of palatable food and obesity. Neuropsychopharmacology, 46:982–991 (*indicates joint contribution) Link
2020
Sayols S, Klassek J, Werner C, Möckel S, Ritz S, Mendez-Lago M and Soshnikova N (2020) Signalling codes for the maintenance and lineage commitment of embryonic gastric epithelial progenitors. Development, 147:dev188839 Link
Schneckenburger H, Richter V, Gelleri M, Ritz S, Vaz Pandolfo R, Schock F, Hase VJ, Birk U and Cremer C (2020) High-resolution deep view microscopy of cells and tissues. Quantum Electron, 50:2–8 Link
Schwirz J*, Yan Y*,#, Franta Z and Schetelig MF# (2020) Bicistronic expression and differential localization of proteins in insect cells and Drosophila suzukii using picornaviral 2A peptides. Insect Biochem Mol Biol, 119:103324 (*indicates joint contribution, #indicates joint correspondance) Link
Wong RP, García-Rodríguez N, Zilio N, Hanulová M and Ulrich HD (2020) Processing of DNA Polymerase-Blocking Lesions during Genome Replication Is Spatially and Temporally Segregated from Replication Forks. Mol Cell, 77:3–16.e4 Link
2019
Bluhm A, Viceconte N, Li F, Rane G, Ritz S, Wang S, Levin M, Shi Y, Kappei D and Butter F (2019) ZBTB10 binds the telomeric variant repeat TTGGGG and interacts with TRF2. Nucleic Acids Res, 47:1896–1907 Link
Liskayová G, Hubčík L, Búcsi A, Fazekaš T, Martínez JC, Devínsky F, Pisárčik M, Hanulová M, Ritz S and Uhríková D (2019) pH-Sensitive N,N-Dimethylalkane-1-amine N-Oxides in DNA delivery: From structure to transfection efficiency. Langmuir, 35:13382–13395 Link
Liu X*, Chen SY*, Chen Q, Yao X, Gelléri M, Ritz S, Kumar S, Cremer C, Landfester K, Müllen K, Parekh S, Narita A and Bonn M (2019) Nanographenes: Ultrastable, switchable, and bright probes for super-resolution microscopy. Angew Chemie Int Ed, 59:496–502 (*indicates joint contribution) Link
Schultheis D, Schwirz J and Frasch M (2019) RNAi screen in Tribolium reveals involvement of F-BAR proteins in myoblast fusion and visceral muscle morphogenesis in insects. G3-Genes Genomes Genet, 9:1141–1151 Link
Schultheis D, Weißkopf M, Schaub C, Ansari S, Dao VA, Grossmann D, Majumdar U, Hakeemi MS, Troelenberg N, Richter T, Schmitt-Engel C, Schwirz J, Ströhlein N, Teuscher M, Bucher G and Frasch M (2019) A large scale systemic RNAi screen in the red flour beetle Tribolium castaneum identifies novel genes involved in insect muscle development. G3-Genes Genomes Genet, 9:1009–1026 Link
2018
Hubčík L, Galliková D, Pullmannová P, Lacinová Ľ, Sulová Z, Hanulová M, Funari SS, Devínsky F and Uhríková D (2018) DNA-DOPE-gemini surfactants complexes at low surface charge density: From structure to transfection efficiency. Gen Physiol Biophys, 37:57–69 Link
Momper R, Steinbrecher J, Dorn M, Rörich I, Bretschneider S, Tonigold M, Ramanan C, Ritz S, Mailänder V, Landfester K and Bannwarth MB (2018) Enhanced photoluminescence properties of a carbon dot system through surface interaction with polymeric nanoparticles. J Colloid Interface Sci, 518:11–20 Link
Reinholz J, Diesler C, Schöttler S, Kokkinopoulou M, Ritz S, Landfester K and Mailänder V (2018) Protein machineries defining pathways of nanocarrier exocytosis and transcytosis. Acta Biomater, 71:432–443 Link
Seiwert D, Witt H, Ritz S, Janshoff A and Paulsen H (2018) The nonbilayer lipid MGDG and the major light-harvesting complex (LHCII) promote membrane stacking in supported lipid bilayers. Biochemistry, 57:2278–2288 Link
2017
Landgraf L, Nordmeyer D, Schmiel P, Gao Q, Ritz S, Gebauer JS, Graß S, Diabaté S, Treuel L, Graf C, Rühl E, Landfester K, Mailänder V, Weiss C, Zellner R and Hilger I (2017) Validation of weak biological effects by round robin experiments: Cytotoxicity/biocompatibility of SiO2 and polymer nanoparticles in HepG2 cells. Sci Rep, 7:4341 Link
Ng DYW, Vill R, Wu Y, Koynov K, Tokura Y, Liu W, Sihler S, Kreyes A, Ritz S, Barth H, Ziener U and Weil T (2017) Directing intracellular supramolecular assembly with N-heteroaromatic quaterthiophene analogues. Nat Commun, 8:1850 Link
2016
Kaloyanova S, Zagranyarski Y, Ritz S, Hanulová M, Koynov K, Vonderheit A, Müllen K and Peneva K (2016) Water-soluble NIR-absorbing rylene chromophores for selective staining of cellular prganelles. J Am Chem Soc, 138:2881–2884 Link
Liu W, Naydenov B, Chakrabortty S, Wuensch B, Hübner K, Ritz S, Cölfen H, Barth H, Koynov K, Qi H, Leiter R, Reuter R, Wrachtrup J, Boldt F, Scheuer J, Kaiser U, Sison M, Lasser T, Tinnefeld P, Jelezko F, Walther P, Wu Y and Weil T (2016) Fluorescent nanodiamond-gold hybrid particles for multimodal optical and electron microscopy cellular imaging. Nano Lett, 16:6236–6244 Link
2015
Lerch S*, Ritz S*, Bley K, Messerschmidt C, Weiss CK, Musyanovych A, Landfester K and Mailänder V (2015) Nanoprobing the acidification process during intracellular uptake and trafficking. Nanomedicine, 11:1585–1596 (*indicates equal contribution) Link
Zaba C, Ritz S, Tan C-WD, Zayni S, Müller M, Reuning U and Sinner E-K (2015) Functional cell adhesion receptors (integrins) in polymeric architectures. ChemBioChem, 16:1740–1743 Link
2014
Boutter J, Huang Y, Marovca B, Vonderheit A, Grotzer MA, Eckert C, Cario G, Wollscheid B, Horvath P, Bornhauser BC and Bourquin J-P (2014) Image-based RNA interference screening reveals an individual dependence of acute lymphoblastic leukemia on stromal cysteine support. Oncotarget, 5:11501–11512 Link
Holloschi A, Ritz S, Schäfer I and Kioschis P (2014) Analysis of huntingtin aggregation by fluorescence and FRET microscopy. Pages 217–215 in: Microscopy: Advances in scientific research and education, vol. 1 (ed. Méndez-Vilas A), Formatex, Badajoz Link
Rämö P, Drewek A, Arrieumerlou C, Beerenwinkel N, Ben-Tekaya H, Cardel B, Casanova A, Conde-Alvarez R, Cossart P, Csúcs G, Eicher S, Emmenlauer M, Greber U, Hardt W-D, Helenius A, Kasper C, Kaufmann A, Kreibich S, Kühbacher A, Kunszt P, Low SH, Mercer J, Mudrak D, Muntwiler S, Pelkmans L, Pizarro-Cerdá J, Podvinec M, Pujadas E, Rinn B, Rouilly V, Schmich F, Siebourg-Polster J, Snijder B, Stebler M, Studer G, Szczurek E, Truttmann M, von Mering C, Vonderheit A, Yakimovich A, Bühlmann P and Dehio C (2014) Simultaneous analysis of large-scale RNAi screens for pathogen entry.BMC Genomics, 15:1162 Link
2013
Persch N, Elhayek A, Welk M, Bruhn A, Grewenig S, Böse K, Kraegeloh A and Weickert J (2013) Enhancing 3-D cell structures in confocal and STED microscopy: A joint model for interpolation, deblurring and anisotropic smoothing. Meas Sci Technol, 24:125703 Link
Publications acknowledging the Microscopy Core Facility
2021
Chongtham MC, Butto T, Mungikar K, Gerber S and Winter J (2021) INTACT vs. FANS for cell-type-specific nuclei sorting: a comprehensive qualitative and quantitative comparison. Int J Mol Sci, 22:5335
Jin E*, Yang Q*, Cheng-Wei J, Chen Q, Landfester K, Bonn M#, Müllen K#, Liu X# and Narita A# (2021) A highly luminescent nitrogen-doped nanographene as an acid- and metal-sensitive fluorophore for optical imaging. J Am Chem Soc, accepted (*indicates joint contribution, #indicates joint correspondance)
Perez-Borrajero C, Podvalnaya N*, Holleis K*, Lichtenberger R, Karaulanov E, Simon B, Basquin J, Hennig J#, Ketting RF# and Falk S# (2021) Structural basis of PETISCO complex assembly during piRNA biogenesis in C. elegans. Genes Dev, 35:1304-1323 (*indicates joint contribution, #indicates joint correspondence)
Placentino M, Jesus Domingues AM, Schreier J, Dietz S, Hellmann S, Albuquerque BF, Butter F and Ketting RF (2021) Intrinsically disordered protein PID‐2 modulates Z granules and is required for heritable piRNA‐induced silencing in the Caenorhabditis elegans embryo. EMBO J, 40:e105280
2020
Dold A*, Han H*, Liu N*, Hildebrandt A, Brüggemann M, Rücklé C, Hänel H, Busch A, Beli P, Zarnack K, König J, Roignant JY# and Lasko P# (2020) Makorin 1 controls embryonic patterning by alleviating Bruno1-mediated repression of oskar translation. PLOS Genet, 16:e1008581 (*indicates joint contribution, #indicates joint correspondence)
Redl S*, de Jesus Domingues AM*, Caspani E, Möckel S, Salvenmoser W, Mendez-Lago M and Ketting RF (2021) Extensive nuclear gyration and pervasive non-genic transcription during primordial germ cell development in zebrafish. Development, 148:dev193060 (*indicates joint contribution)
Vydzhak O*, Bender K*, Klermund J, Busch A, Reimann S and Luke B (2020) Checkpoint adaptation in recombination-deficient cells drives aneuploidy and resistance to genotoxic agents. DNA Repair, 95:102939 (*indicates joint contribution)
2019
Arab K, Karaulanov E, Musheev M, Trnka P, Schäfer A, Grummt I# and Niehrs C# (2019) GADD45A binds R-loops and recruits TET1 to CpG island promoters. Nat Genet, 51:217–223 (#indicates joint correspondence)
Gothe HJ, Bouwman BAM*, Gusmao EG*, Piccinno R, Petrosino G, Sayols S, Drechsel O, Minneker V, Josipovic N, Mizi A, Nielsen CF, Wagner EM, Takeda S, Sasanuma H, Hudson DF, Kindler T, Baranello L, Papantonis A*, Crosetto N* and Roukos V (2019) Spatial chromosome folding and active transcription drive DNA fragility and formation of oncogenic MLL translocations. Mol Cell, 75:267-283.e12 (*indicates joint contribution)
Gronke K, Hernández PP, Klose CSN, Kofoed-Branzk M, Guendel F, Witkowski M, Tizian C, Amann L, Schumacher F, Glatt H, Triantafyllopoulou A and Diefenbach A (2019) Interleukin-22 protects intestinal stem cells against genotoxic stress.Nature, 566:249–253
Han D*, Schomacher L*#, Schüle KM*, Mallick M, Musheev MU, Karaulanov E, Krebs L, von Seggern A and Niehrs C# (2019) NEIL1 and NEIL2 DNA glycosylases protect neural crest development against mitochondrial oxidative stress. eLife, 8:e49044 (*indicates joint contribution, #indicates joint correspondence)
Hildebrandt A, Brüggemann M, Rücklé C, Boerner S, Heidelberger JB, Busch A, Hänel H, Voigt A, Möckel MM, Ebersberger S, Scholz A, Dold A, Schmid T, Ebersberger I, Roignant JY, Zarnack K#, König J# and Beli P# (2019) The RNA-binding ubiquitin ligase MKRN1 functions in ribosome-associated quality control of poly(A) translation. Genome Biol, 20:216 (#indicates joint correspondence)
Schüle KM*, Leichsenring M*, Andreani T, Vastolo V, Mallick M, Musheev MU, Karaulanov E and Niehrs C (2019) GADD45 promotes locus-specific DNA demethylation and 2C cycling in embryonic stem cells. Genes Dev, 33:782–798 (*indicates joint contribution)
2018
Almeida MV, Dietz S, Redl S, Karaulanov E, Hildebrandt A, Renz C, Ulrich HD, König J, Butter F and Ketting RF (2018) GTSF‐1 is required for formation of a functional RNA‐dependent RNA polymerase complex in Caenorhabditis elegans. EMBO J, 37: e99325
Fritzsch C*, Baumgärtner S*, Kuban M, Steinshorn D, Reid G# and Legewie S# (2018) Estrogen‐dependent control and cell‐to‐cell variability of transcriptional bursting. Mol Syst Biol, 14: e7678 (*indicates joint contribution,#indicates joint correspondence)
García‐Rodríguez N, Morawska M, Wong RP, Daigaku Y and Ulrich HD (2018) Spatial separation between replisome‐ and template‐induced replication stress signaling. EMBO J, 37: e98369
Heidelberger JB, Voigt A, Borisova ME, Petrosino G, Ruf S, Wagner SA and Beli P (2018) Proteomic profiling of VCP substrates links VCP to K6‐linked ubiquitylation and c‐Myc function.EMBO Rep, 19:187-381
Kaymak A, Sayols S, Papadopoulu T and Richly H (2018) Role for the transcriptional activator ZRF1 in early metastatic events in breast cancer progression and endocrine resistance. Oncotarget, 9: 28666–28690
Moscariello P, Ng DYW, Jansen M, Weil T, Luhmann HJ and Hedrich J (2018) Brain delivery of multifunctional dendrimer protein bioconjugates. Adv Sci, 5:1700897
Nayak T, Trotter J and Sakry D (2018) The intracellular cleavage product of the NG2 proteoglycan modulates translation and cell-cycle kinetics via effects on mTORC1/FMRP Signaling.Front Cell Neurosci, 12:231
Roovers EF*, Kaaij LJT*, Redl S, Bronkhorst AW, Wiebrands K, de Jesus Domingues AM, Huang HY, Han CT, Riemer S, Dosch R, Salvenmoser W, Grün D, Butter F, van Oudenaarden A and Ketting RF (2018) Tdrd6a regulates the aggregation of Buc into functional subcellular compartments that drive germ cell specification. Dev Cell, 46:285–301.e9 (*indicates joint contribution)
Schink A, Neumann J, Leifke AL, Ziegler K, Fröhlich-Nowoisky J, Cremer C, Thines E, Weber B, Pöschl U, Schuppan D and Lucas K (2018) Screening of herbal extracts for TLR2- and TLR4-dependent anti-inflammatory effects. PLoS ONE, 13:e0203907
Tiwari N, Pataskar A, Péron S, Thakurela S, Sahu SK, Figueres-Oñate M, Marichal N, López-Mascaraque L, Tiwari VK and Berninger B (2018) Stage-Specific transcription factors drive astrogliogenesis by remodeling gene regulatory landscapes.Cell Stem Cell, 23: 557–571.e8
Zimmermann T, Maroso M, Beer A, Baddenhausen S, Ludewig S, Fan W, Vennin C, Loch S, Berninger B, Hofmann C, Korte M, Soltesz I, Lutz B and Leschik J (2018) Neural stem cell lineage-specific cannabinoid type-1 receptor regulates neurogenesis and plasticity in the adult mouse hippocampus. Cerebral Cortex, 28, 4458–4471
2017
Blanquie O, Yang J-W, Kilb W, Sharopov S, Sinning A and Luhmann HJ (2017) Electrical activity controls area-specific expression of neuronal apoptosis in the developing mouse cerebral cortex. eLife, 6: 1-21
Chitale S and Richly H (2017) Nuclear organization of nucleotide excision repair is mediated by RING1B dependent H2A-ubiquitylation. Oncotarget, 8: 30870-30887
Dinges N, Morin V, Kreim N, Southall TD and Roignant JY (2017) Comprehensive characterization of the complex lola locus reveals a novel role in the octopaminergic pathway via tyramine beta-hydroxylase regulation. Cell Rep, 21:2911–2925
Dzama MM, Nigmatullina L, Sayols S, Kreim N and Soshnikova N (2017) Distinct populations of embryonic epithelial progenitors generate Lgr5+ intestinal stem cells. Dev Biol, 432: 258-264
Graf M, Bonetti D, Lockhart A, Serhal K, Kellner V, Maicher A, Jolivet P, Teixeira MT and Luke B (2017) Telomere length determines TERRA and R-Loop regulation through the cell cycle. Cell, 170: 72-85
Kazakevych J, Sayols S, Messner B, Krienke C and Soshnikova N (2017) Dynamic changes in chromatin states during specification and differentiation of adult intestinal stem cells. Nucleic Acids Res, 45: 5770-5784
Lebedeva S, de Jesus Domingues AM, Butter F and Ketting RF (2017) Characterization of genetic loss-of-function of Fus in zebrafish. RNA Biol, 14: 29-35
Navandar M, Garding A, Kumar Sahu S, Pataskar A, Schick S and Tiwari VK (2017) ERK signalling modulates epigenome to drive epithelial to mesenchymal transition. Oncotarget, 8: 29269-29281
Nigmatullina L, Norkin M, Dzama MM, Messner B, Sayols S and Soshnikova N (2017) Id2 controls specification of Lgr5(+) intestinal stem cell progenitors during gut development. EMBO J, 36: 869-885
Sahu SK, Tiwari N, Pataskar A, Zhuang Y, Borisova M, Diken M, Strand S, Beli P and Tiwari VK (2017) FBXO32 promotes microenvironment underlying epithelial-mesenchymal transition via CtBP1 during tumour metastasis and brain development. Nat Commun, 8: 1523
Szczurek A, Klewes L, Xing J, Gourram A, Birk U, Knecht H, Dobrucki JW, Mai S and Cremer C (2017) Imaging chromatin nanostructure with binding-activated localization microscopy based on DNA structure fluctuations. Nucleic Acids Res, 45: e56
Wilhelm T, Byrne J, Medina R, Kolundžić E, Geisinger J, Hajduskova M, Tursun B and Richly H (2017) Neuronal inhibition of the autophagy nucleation complex extends life span in post-reproductive C. elegans. Genes Dev, 31: 1561-1572
2016
Blanquie O, Liebmann L, Hübner CA, Luhmann HJ and Sinning A (2016) NKCC1-mediated GABAergic signaling promotes postnatal Cell death in neocortical Cajal-Retzius cells. Cereb Cortex, 27: 1644-1659
Kaymak A and Richly H (2016) Zrf1 controls mesoderm lineage genes and cardiomyocyte differentiation. Cell Cycle, 15: 3306-3317
2015
Hirsch M and Helm M (2015) Live cell imaging of duplex siRNA intracellular trafficking. Nucleic Acids Res, 43: 4650-60
Kirmes I, Szczurek A, Prakash K, Charapitsa I, Heiser C, Musheev M, Schock F, Fornalczyk K, Ma D, Birk U, Cremer C and Reid G (2015) A transient ischemic environment induces reversible compaction of chromatin. Genome Biology, 16: 246
Roovers EF, Rosenkranz D, Mahdipour M, Han CT, He N, de Sousa Lopes SMC, van der Westerlaken LA, Zischler H, Butter F, Roelen BA and Ketting RF (2015) Piwi proteins and piRNAs in mammalian oocytes and early embryos. Cell Reports, 10: 2069-2082
Sahu SK, Garding A, Tiwari N, Thakurela S, Toedling J, Gebhard S, Ortega F, Schmarowski N, Berninger B, Nitsch R, Schmidt M and Tiwari V (2015) JNK-dependent gene regulatory circuitry governs mesenchymal fate. EMBO J, 34: 2162-2181. DOI: 10.15252/embj.201490693
Sakry D, Yigit H, Dimou L and Trotter J (2015) Oligodendrocyte precursor cells synthesize neuromodulatory factors. PLoS One, 10: e0127222
Stangenberg R, Wu Y, Hedrich J, Kurzbach D, Wehner D, Weidinger G, Kuan SL, Jansen MI, Jelezko F, Luhmann HJ, Hinderberger D, Weil T and Müllen K (2015) A polyphenylene dendrimer drug transporter with precisely positioned amphiphilic surface patches. Adv Healthc Mater, 4: 377-384
2014
Bühler J, Gietzen S, Reuter A, Kappel C, Fischer K, Decker S, Schäffel D, Koynov K, Bros M, Tubbe I, Grabbe S and Schmidt M (2014) Selective uptake of cylindrical poly(2-oxazoline) brush-antidec205 antibody-ova antigen conjugates into dec-positive dendritic cells and subsequent t-cell activation. Chemistry, 20: 12405-12410
Fritz T, Hirsch M, Richter FC, Müller SS, Hofmann AM, Rusitzka KAK, Markl J, Massing U, Frey H and Helm M (2014) Click modification of multifunctional liposomes bearing hyperbranched polyether chains. Biomacromolecules, 15: 2440-2448
Hamm R, Chen YR, Seo EJ, Zeino M, Wu CF, Müller R, and Yang NS and Efferth T (2014) Induction of cholesterol biosynthesis by archazolid B in {T24} bladder cancer cells. Biochem Pharmacol, 91: 18-30
Hamm R, Zeino M, Frewert S and Efferth T (2014) Up-regulation of cholesterol associated genes as novel resistance mechanism in glioblastoma cells in response to archazolid B. Toxicol Appl Pharmacol, 281: 78-86
Malone CD, Mestdagh C, Akhtar J, Kreim N, Deinhard P, Sachidanandam R, Treisman J and Roignant JY (2014) The exon junction complex controls transposable element activity by ensuring faithful splicing of the piwi transcript. Genes Dev, 28: 1786-1799
2013
Thakurela S, Garding A, Jung J, Schübeler D, Burger L and Tiwari VK (2013) Gene regulation and priming by topoisomerase IIα in embryonic stem cells. Nat Commun, 4: 2478
Tiwari N, Tiwari V, Waldmeier L, Balwierz P, Arnold P, Pachkov M, Meyer-Schaller N, Schübeler D, van Nimwegen E and Christofori G (2013) Sox4 is a master regulator of epithelial-mesenchymal transition by controlling Ezh2 expression and epigenetic reprogramming. Cancer Cell, 23: 768-783
Zehender CM, Librizzi L, Hedrich J, Bauer NM, Angamo EA, De Curtis M and Luhmann HJ (2013) Moderate hypoxia followed by reoxygenation results in blood-brain barrier breakdown via oxidative stress-dependent tight-junction protein disruption. PLoS One, 8: e82823
Zehender CM, Tsohataridis S, Luhmann HJ and Yang JW (2013) Developmental switch inneurovascular coupling in the immature rodent barrel cortex. PLoS One, 8: e80749
Zehender CM, Wedler HE and Luhmann HJ (2013) A novel in vitro model to study pericytes in the neurovascular unit of the developing cortex. PLoS One, 8: e81637
2012
Gierl MS, Gruhn H, von Seggern A, Maltry N and Niehrs C (2012) GADD45G functions in male sex determination by promoting p38 signaling and sry expression. Dev Cell, 23: 1032-1042