The Institute of Molecular Biology (IMB)

Welcome to IMB! We are a modern research centre that brings together leading scientists from all over the world. Our researchers tackle ambitious projects at the interface of epigenetics, genome stability, ageing & RNA biology.

About us
Who we are, where we are & what we do...
Research
Our scientists & what they are working on...
Core Facilities
State-of-the-art technologies & services...
Students & Postdocs
Training programmes we offer junior researchers...
Seminars & Events
Conferences, meetings, workshops & more...
Careers
Current opportunities at IMB...

The funds will be used to establish a new doctoral training programme called CoAGE (“Cohorts for Healthy Ageing”)

The conference will be on "The Evil within: Regulation & Repair of Endogenous DNA Damage"

Congratulations to Claudia!

18 Sep 2025
Course
Building a strategic approach to research funding
Dr Gunnar Seemann
18 Sep 2025
Seminar | SFB 1361 Seminar
Regulation of somatic hypermutation by higher order chromatin structure
Dr Rushad Pavri

Access the full IMB events calendar by clicking here

Recent Publications

Jul 2025 | Trends Genet | König
m6A in the coding sequence: linking deposition, translation, and decay.
Jul 2025 | EMBO Rep | Ketting
A genetic framework for RNAi inheritance in Caenorhabditis elegans.
Jun 2025 | Elife | König
Modifying gene expression through passive forces.
Jun 2025 | Nucleic Acids Res | Butter | Ketting
ERH regulates type II interferon immune signaling through post-transcriptional regulation of JAK2…
Jun 2025 | ChemMedChem | Stelzl
Proton first: rationalizing a proton transfer in a protein-fragment complex.
Jun 2025 | Genes Dev | Keller Valsecchi
Sex-specific transcriptome dynamics of Anopheles gambiae during embryonic development.
Jun 2025 | Cell Chem Biol | Dormann
Two sides of a co(i)ndensate.
Jun 2025 | Genes Dev | Beli
The USP11/TCEAL1 complex promotes transcription elongation to sustain oncogenic gene expression in…
May 2025 | DNA Repair | Ulrich
Reversible association of ubiquitin with PCNA is important for template switching in S. cerevisiae.
May 2025 | eGastroenterology | Vieira-Silva
Dietary convergence induces individual responses in faecal microbiome composition.

A centre for basic & clinical research on ageing & age-related disease
with Mainz University & its Medical Center, the Leibniz Institute for Resilience Research & TRON
A joint initiative on the mechanisms underlying robustness & longevity
with groups at Mainz University
A joint PhD programme to discover new ways to understand & treat age-related diseases
with Mainz University & its Medical Center
A joint PhD programme to understand why diseases are more common in old age and how we can age healthily
with Helmholtz Munich, the German Center for Neurodegenerative Diseases (DZNE), the University Medical Center Hamburg-Eppendorf, Leipzig University, Greifswald University Hospital, and Mainz University's Medical Center
The largest network on DNA repair & genome stability in Germany
with groups in Mainz, Darmstadt, Frankfurt & Munich
An initiative bridging the polymer & life sciences to understand biological processes such as ageing
with Mainz University, its Medical Center & the Max Planck Institute for Polymer Research
IMB’s flagship PhD training programme on epigenetics, genome stability & ageing
with Mainz University & its Medical Center
A DFG-funded PhD programme on how RNA processes contribute to robustness & resilience
with groups from Mainz University & its Medical Center
A DFG-funded PhD programme on the evolution of gene regulatory networks underlying phenotype & lifespan
with Mainz University’s Faculty of Biology

News

IMB and the Centre for Healthy Ageing (CHA) receive €1.3 million to study the causes of age-related diseases

Save the date for the IMB/SFB 1361 Conference in March 2026!

Claudia Keller Valsecchi recieves the Friedrich Miescher Award 2025

Upcoming Events

18 Sep 2025

18 Sep 2025

Joint Research Initiatives

A centre for basic & clinical research on ageing & age-related disease

A joint initiative on the mechanisms underlying robustness & longevity

A joint PhD programme to discover new ways to understand & treat age-related diseases

A joint PhD programme to understand why diseases are more common in old age and how we can age healthily

The largest network on DNA repair & genome stability in Germany

An initiative bridging the polymer & life sciences to understand biological processes such as ageing

IMB’s flagship PhD training programme on epigenetics, genome stability & ageing

A DFG-funded PhD programme on how RNA processes contribute to robustness & resilience

A DFG-funded PhD programme on the evolution of gene regulatory networks underlying phenotype & lifespan